Legend for E. coli typing (bovine):
Genes encoding the following gene products:
Adhesines | Virulence factors and toxins |
F4 (F4 fimbriae) | Intimine (required for the penetration into epithelial cells) |
F5 (F5 fimbriae) | LTI (heat labile enterotoxin) |
F6 (F6 fimbriae) | STI (heat stable enterotoxin) |
F17 (F17 fimbriae) | STII (heat stable enterotoxin) |
F41 (F41 fimbriae) | EAST-I (heat stable enterotoxin) |
fimH (Type 1 fimbriae) | stx1 (Shiga toxin variant 1) |
fimA (Type 1 fimbriae) | stx2 (Shiga toxin variant 2) |
papC (P fimbriae) | cdtB (cytolethal distending toxin) |
aidA (AIDA-I autotransporter adhesine) | cnf1 (zytotoxic nekrotising factor type 1) |
paa (porcine adherence factor) | iucD (required for the synthesis of iron complexing agents) |
escV (type III sekretions system) | |
pic (serin protease autotransporter) |
Pathogenic isolates generally carry a combination of fimbriae / adhesins and toxins. Several toxins and adhesins can be present at the same time and in different combinations.